多个技术并行推进疫苗研发:不会成为“马后炮”!

2020-02-16 22:02:16 来源: 科技日报 作者: 张佳星

科技日报记者 张佳星

17NIANQIAN,TURUQILAIDESARSBINGDUYUCAIGUIGUODEGUOYAOZHONGSHENGJITUANZONGCAI、DANGWEISHUJIYANGXIAOMINGDALEYICHANG“ZAOYUZHAN”。ZUOWEIYIMIAO“LAOBING”,TASHENZHITIAOJIAN、PINGTAIBUZUSHIDANGSHIDEKEYANGUOQING,YIMIAOYANFASHIJIANZHANG、YI10NIANJI、SHI“YUANSHUI”。

17NIANHOU,YINGZHANXINGUANBINGDU,TASHUO:GUOQUSHIJINIANDEGUOJIAKEJIZHICHENG,RANGZHONGGUODEYIMIAOYANFAJISHU、PINGTAI、TIXIZHUJIANHE黄金配资 JIEGUI,YIMIAOCONGYANFADAOSHENGCHANSHIGEZHANGLIANTIAO,WOGUODEZHIDUYOUSHIJIANGNINGJIEGEFANGLILIANG,ZAIANQUAN、YOUXIAODEQIANTIXIA,ZUIDAXIANDUSUODUANLIUCHENG。

弘业股份YOUSHUJUXIANSHI,YINGZHANSARS,CONGGONGBUBINGDUDEJIYINZUDAOYANFACHUKEYONGYURENTISHIYANDEYIMIAO,RENLEIYONGSHIYUE20GEYUE;YINGZHANZHAIKABINGDUZHEIYIGUOCHENGYONGLE6GEYUE;ERXIANZAI,ZHEIGESHIJIANHUOXUJIANGGENGDUAN。

弘业股份“YIMIAOSHIJIEZHONGJINJIANKANGRENDESHENTILI,MEIYIZHIYIMIAODOUBIXUJINGLIKEXUE、YANJIN、GUIFANDEYANFA;YIQINGDANGQIAN,YANFAYOUYAOYUBINGDUPINSUDU。”YANGXIAOMINGDALEGEXINGXIANGDEBIYU,XINGUANBINGDUYIMIAODEYANFAJIURUTONG“GAOSUZOUGANGSI”,JIYAOZHENGFENDUOMIAOYOUYAOYIRENMINDEJIANKANGANQUANWEIZHUNSHENG,SIHAOBUYUYUE。

1YUE22RI,GUOJIAKEJIBU“XINXINGGUANZHUANGBINGDUGANRANDEFEIYANYIQINGKEJIYINGDUI”DIYIPIYINGJIGONGGUANXIANGMUQIDONG,KUAISUYIMIAOYANFASHIZHONGYAOYANFARENWUZHIYI。GUOJIACHENGLILEKEJIGONGGUANZU,FAHUIQUANGUOYIPANQIDETIZHIYOUSHI,GEZHONGZIYUANZONGHELIYONG,YANFA、JIANGUAN、LINCHUANG、SHENGCHANTONGBUXINGDONG,YEYIJIRI,QUANLIYIFU,YIZUIKUAIDESHIJIANZAORIYANFACHUXINGUANYIMIAO。


多项技术路线同时着力疫苗研发

为了提高针对新型冠状病毒研发生产的成功率,中国生物技术发展中心副主任孙燕荣在2月4日国家卫健委配资开户 发布会上表示,我国科技界正在并行推进多个技术进行疫苗研究,以便能够早日实现疫苗研发的成功。

“CHUANTONGDEFANGFASHIMIEHUOYIMIAO。”YANGXIAOMINGSHUO,“XIANZAIHAIYOUDUOGEXINDEJISHULUXIAN,BIRUYADANWEIYIMIAO、BINGDUZAITIYIMIAO,DNAYIMIAOHUOmRNAYIMIAODENG。”

CHUANTONGDEMIEHUOYIMIAOGONGYI“YUANZHIYUANWEI”,SHIYONGBEISHAMIEDEBINGDUCIJIJIANKANGRENTINEIDEMIANYIXITONG,CHANSHENGCHUZHENDUIXINGUANBINGDUDEKANGTI,DADAOYUFANGJIBINGMUDE。

弘业股份“MIEHUOYIMIAOSHIJIANGXINGUANBINGDUPEIYANGHOU,JINXINGMIEHUOHECHUNHUAZHIBEICHENGYIMIAO。MIEHUOYIMIAOKEYOUZHENGGEBINGDUZUCHENG,YEKEYOUQILIEJIEPIANDUANZUCHENG。”YANGXIAOMINGBIAOSHI,ZAIMIANDUIXINFACHUANRANBINGSHI,MIEHUOYIMIAOYANFADEGONGYILUXIANBIJIAOCHENGSHU,GEGEZHILIANGKONGZHIDIANHEPINGJIAFANGFAMINGQUE,GUIMOHUASHENGCHANGONGYIDUIJIERONGYI。

ZHONGZUDANBAIYIMIAOZEGENGXIANGSHIYONGBINGDUDE“RENZAOLAXIANG(YIBUFEN)”,YOUDAORENTICHANSHENGMIANYIFANYING。

ZHONGZUDANBAIYIMIAOSHIJIANGXINGUANBINGDUDEBUFENGONGNENGJIYINZAIXIBAOHUOWEISHENGWUZHONGDALIANGBIAODA,JINGGUOCHUNHUAHOUZHIBEIDEYIMIAO。ZHONGGUOKEXUEYUANWEISHENGWUYANJIUSUOYANJIUYUANYANJINGHUASUOZAITUANDUIFUZEZHONGZUDANBAIYADANWEIYIMIAOYANJIU,TACIQIANDUIMEITIBIAOSHI,“TUANDUIYIQIANZUOGUOMERS(ZHONGDONGHUXIZONGHEZHENG)YIMIAO,XIAOGUOHENHAO,XIANZAISHIANZHAOZHEIGEMOSHILAIJINXINGXINGUANYIMIAODEYANJIU。WOMENZHENGZAIYIXIAOSHIWEIDANWEIXIANGQIANTUIJIN,ZHENGFENDUOMIAO。”

mRNAYIMIAOBADANBAIHECHENGDEBUFENJIAOJIRENTI,XIAOLVGENGGAO,SHIYONGBINGDUDE“RENZAOLAXIANG”DE“SHEJITUZHI”XINGCHENGMIANYIJIYI。

“mRNAYIMIAOSHIZHIZAITIWAIHECHENGBINGDUDEXIANGGUANXULIEmRNA,JIANGmRNACHUANDIDAORENTIXIBAONEIXINGCHENGMIANYI。”SHANGHAISIWEIFUZERENLIHANGWENBIAOSHI,mRNAYIMIAODESHENGCHANWUXUYILAIXIBAOKUOZENGDEGUOCHENG,SHENGCHANGENGRONGYIFANGDA。ERQIEXIANQIHECHENGKUAI,YIDANZAIHUOTIDONGWUZHONGYANZHENGNENGGOUCHANSHENGYOUXIAOKANGYUANJIANGHENKUAIXIANGXIATUIJIN。

LINGYIZHONGBEICHENGWEIBINGDUZAITIYIMIAODEJISHU,TARANG“CONGLIANG”DEBINGDUXINGCHENGMIANYIJIYI。TONGGUOZAITIWAIGAIZAOBINGDU,ZAIXIBAONEIDALIANGKUOZENG、CHUNHUAHOUZHIBEIDEBINGDUZAITIYIMIAO,SHIBABINGDUJINXINGLE“YIHUAJIEMU”DEGAIZAO,SHIQI“CONGLIANG”,RANHOUZAIJIANKANGRENTINEIXINGCHENGMIANYIJIYI。XIANGMUFUZERENZHONGGUOGONGCHENGYUANYUANSHI、JUNSHIYIXUEYANJIUYUANYANJIUYUANCHENWEISHUODEXINGXIANG:ZAI“XUEXI”BINGDUDEQIANTIXIA,DUIBINGDUJINXING“SHOUSHU”,YONGYIHUAJIEMUDEFANGFA,GAIZAOCHUYIGEWOMENXUYAODEZAITIBINGDU,BINGZHURURENTICHANSHENGMIANYI。

ZONGSHANGSUOSHU,JIZHONGJISHULUXIAN,WULUNSHI“YUANZHIYUANWEI”(MIEHUOYIMIAO),HAISHI“LAXIANG”(ZHONGZUDANBAIYIMIAO),HAISHI“TUZHI”(mRNAYIMIAO),ZAIHUOZHEYONG“CONGLIANG”BINGDU(BINGDUZAITIYIMIAO),DOUSHIWEILEXIANGJIANKANGDERENTIYINRUYIZHONGWUHAIHUOZHEYOUQINGDUYINGXIANGDEWUZHI,RANGSHENTIXINGCHENGMIANYIJIYI,ZAIYUDAOBINGDUSHI,JIFAMIANYIXITONGZUOZHANQUSHENG。


多条赛道给出时间表 离全民防疫越来越近

2月1日,科技部启动的“新型冠状病毒感染的肺炎疫情科技应对”中关于疫苗研发的应急攻关项目经过前期摸底和申报,正式开启。每个技术路线都由多个单位形成合力,从企业到科研院所再到高等级生物安全实验室等全面开启夜以继日的研发工作。

“2YUE6HAO,WOMENYIJINGWANCHENGLEDIYIPISHIYANYONGmRNAYIMIAODESHENGCHAN,CHANPINZIJIANHEGE,BAOZHUANGmRNADENAMIKELIFEICHANGJUNYI,DADAOXIANGGUANBIAOZHUN,YEJINGGUOLEXIANGYINGDEJIANDING。”JUNSHIKEXUEYUANJUNSHIYIXUEYANJIUYUANXIANGMUFUZERENJIESHAO,2YUE7RI,mRNAYIMIAOJIEZHONGDAOSHIYANXIAOSHUSHENSHANG,KAISHIMIANYIYUANXINGPINGJIA。ZHEIBUFENJIANCEmRNAYIMIAOZUOWEI“TUZHI”JINRUZHENGCHANGXIAOSHUZHIHOU,JITIYOUMEIYOUGENJU“TUZHI”HECHENGCHUTEDINGDEDANBAIZHI,QIDAOKANGYUANDEZUOYONG。RUGUOKANGYUANHEXINGUANBINGDUKANGYUANXIANGSI,NEIMECAIHUIXINGCHENGXINGUANBINGDUDEMIANYIJIYI。

弘业股份2YUE11RI,XIANGGUANDANWEIQIDONGLEZAIDONGWUMOXINGSHANGDEGONGDUSHIYAN,KANJIEZHONGLEZHEIZHONGYIMIAODEXIAOSHUSHIFOUHUIZAIXINGUANBINGDUGONGJIHOURENGNENGJIANKANG,BINGYUWEIJIEZHONGYIMIAODEXIAOSHUJINXINGDUIBI。

XIANGMUXIANGGUANFUZERENBIAOSHI,MUQIANmRNADEYANFAJINCHENGYIJINGYUANCHAOYUQI,ZHANSHILEKUAISUYINGDANENGLI,WEILAIHAIXUYAOGENGDUODEDONGWUSHIYAN,YIGEYUEZHINEIKEYIJIBENSHANGMINGQUEBUTONGDEmRNAYIMIAONAZHONGBAOHULIZUIJIA。CHUBUJIHUA4YUEJIANGJINRUANQUANPINGJIAJIEDUAN,TONGGUOHOUJINRULINCHUANGSHIYANJIEDUAN。

弘业股份ZAISHENPINGSHENPIFANGMIANXUYAOXIEDIAODUOBUMENQIANQIJINRU,JIASUTUIJIN;SHENGCHANFANGMIAN,MUQIANMANZUYIMIAOSHENGCHANYAOQIUDESHENGCHANGUIMOKEWANCHENG1WANRENFEN/TIAN,XUYAOZAIQUANGUOBUTONGDEDIFANGJIANLImRNAYIMIAODESHENGCHANXIAN。

弘业股份ZHONGZUDANBAIYIMIAOFANGMIAN,XINGUANBINGDUZHONGDESDANBAISHIZUIZHUYAODEKANGYUANDANBAI。“NENGGOUJIFAMIANYILIDEZHIYOUYIXIAOBUFEN。”YANJINGHUAJIESHI,MUQIANDEGONGZUOBAZHEIGEZUIZHONGYAODEBUFENNACHULAI,QITAKENENGCHANSHENGFUZUOYONGDEKANGTIDEBUFENQUDIAO,BINGSHEJILETIGAOMIANYIHUOXINGDEQUANXINJIEGOU。

MUQIAN,GAILEIYIMIAOYIJINGWANCHENGLEKANGYUANSHEJI、SHAIXUAN、XIAOLIANGBIAODAHEXIAOSHUMIANYIDENGSHIYAN,ZHENGZAIJINXINGYOUXIAOXINGPINGJIADENGYANJIU,YUJI3YUEDICHUBUHUODEDONGWUYOUXIAOXINGPINGJIAJIEGUO,4YUEJIANLISHENGCHANGONGYI,5YUEHUODEFUHEZHUCEYAOQIUDEYIMIAOCHANPIN。

弘业股份BINGDUZAITIYIMIAOFANGMIAN,XIANGGUANFUZERENBIAOSHI,DIYIBUTONGGUOZHONGZUXIANBINGDULAIBIAODAXINGUANBINGDUDESDANBAIJIYIN。DIERBUZHIBEIDUZHONGKU。RANHOUZAIZHONGZUJIANDINGHEGE、JINXINGZHONGSHIFANGDA、GONGYISHEJIDENG。TONGSHIZAIDONGWUMOXINGSHANGLAIPINGJIADONGWUBAOHUXING。MUQIANGAIYANJIUCHUYUBINGDUDUZHONGDEGOUJIANJIEDUAN,YIJINGZHONGZUCHUBIAODAKANGYUANNENGLIGAOXIAODEDUZHU,LIZHENG4YUE30RINENGGOUSHENBAOLINCHUANG。

CHUANTONGDEMIEHUOYIMIAOFANGMIAN,ZHONGGUOSHENGWUXIANGGUANFUZERENJIESHAO,MUQIANYIWANCHENGBINGDUJIEZHONGXIBAO,WANCHENGLEBINGDUXIBAODESHIYINGXINGCHUANDAIPEIYANG,BINGHEZUOKAIZHANLEGANRANXINGDONGWUMOXINGDEJIANLIGONGZUO。TONGSHIBINGXINGKAIZHANLEJIANCEJIANDINGFANGFADEJIANLIGONGZUO,WANCHENGXIAYOUCHUNHUAFANGFADEJIANLI,BINGCHUBUJIANLIBINGDUMIEHUOYIMIAODEZHILIANGBIAOZHUN,YIDANMIEHUOYIMIAOSHAIXUANWANCHENG,HOUMIANDEGONGZUOJIANGSHUIDAOQUCHENG。MUQIANJIHUA9YUEZHONGXIAXUNSHENGCHANCHUHEGEYANGPINSHENBAOLINCHUANGSHIYAN。


“高速”开跑:少不了过往的“战疫”积累

“多个技术路线并行就是为了早点研制出能够抗击疫情的疫苗。”杨晓明说,用“心急如焚”来形容各界对疫苗的期待丝毫不过,但对于科学家来说,除了要“快”还要“好”,即尊重科学规律,实现安全、有效。

ZENMECAINENGHAO?GUOWANGDEYIMIAOYANFAJINGLIHEPINGTAI,JIANGDADASUODUANYANFASHIJIAN。

弘业股份“FEIDIANSHIQI,SARSBINGDUYIMIAOYIJINGTUIJINDAOLELINCHUANGSHIYANJIEDUAN。”YANGXIAOMINGSHUO,BENCIXINGUANBINGDUYUSARSBINGDUYOUXIANGSIXING,ZUIQIMASHITONGLEIDE,YINCIDUIYUSARSBINGDUDEMIEHUOYIMIAODESHENGCHANLUJING、JICHUSHUJUHESHIJIANJINGYAN,DUIYUXIANXINGYANJIUZHIGUANZHONGYAO。

弘业股份DUIYUMIEHUOYIMIAOLAISHUO,SHEJIANQUANXINGFANGMIANDEYIMIAOZHUDEPEIYU、XIBAOJIZHIDESHIYING、GUIMOHUADEZHIZAO,GONGYIZHILIANGWENDINGXINGDETANSUODENGGONGZUOYOULECHUBUDEFANGXIANG,KEWEIYIMIAOYANFASUODUAN2-3NIANSHIJIAN。SUOYOUZHEIXIEJISHUPINGTAI,WEIMIEHUOYIMIAODE“GAOSU”KAIPAODIANDINGLEJICHU。

ZHONGZUDANBAIYIMIAOFANGMIAN,WANSHIJUBEI,ZHIQIANDONGFENG。ZHONGKEYUANWEISHENGWUSUOTXIBAOMIANYIDIAOKONGYANJIUZUYANJIUYUANMENGSONGDONGBIAOSHI,ZAIYIMIAOZUOJIFANGMIAN,TUANDUIYANJIUCHULEMUQIANWEIYIYONGYULINCHUANGDETIANRANZUOJI——gp96JIEDAODETXIBAOZUOJI,LIANGNIANQIANYIKAISHIZHONGSHIHUASHENGCHAN。ZHONGZUDANBAIYIMIAOFANGMIANYIDANZHAODAOLEMIANYIXIBAODE“JIFADANBAI”,YIGEYUEZHINEIKEJINRUDONGWUSHIYANJIEDUAN。

BINGDUZAITIYIMIAOFANGMIAN,ZHONGGUOCHUYU“LINGPAO”DIWEI。2014NIAN,DUANDUANSIGEYUE,CHENWEITUANDUIJIANGSHIJIESHANGSHOUGEYIXIANBINGDUWEIZAITIDEAIBOLAYIMIAOTUIRULELINCHUANGYANJIU。JINGGUOYANJINDE1、2、3QILINCHUANGSHIYAN,YU2017NIAN10YUE19RICHENGWEIQUANQIUSHOUGEAIBOLAYIMIAOHUOPIXINYAO。CHENWEIZAIJIESHOUMEITICAIFANGSHIBIAOSHI:WOXIANGXINWOGUOKEYANRENYUANDESUDU,YIMIAOBUHUISHI“MAHOUPAO”。


从串联到并联:“国字号”平台推进疫苗检定和生产

GUIMOHUADEPEIYANGJISHUPINGTAI、GUIMOHUACHUNHUAPINGTAI、ZHILIANGJIANCEPINGGUTIXI……KEYANGONGGUANHOU,WULUNNAZHONGJISHULUXIANCHULAIDEYIMIAODOUXUYAOTUPOSHENGCHANGUAN。

弘业股份“YIMIAOSHIXUYAODAGUIMOSHENGCHANDE,ZAIHAODEYIMIAO,RUGUOCHANLIANGBUGOU,BUNENGGUANGFANSHIYONG,YENANXINGCHENGRENQUNDEMIANYIBAOHUPINGZHANG。”YANGXIAOMINGSHUO,ZAIGUOJIAZHONGDIANZHICHENGJIHUAHE863JIHUADEZHICHIXIA,ZAI“SHIWU”“SHIYIWU”“SHIERWU”QIJIANDEKEJITOURU,GEGEZHUANYEYANJIUYUANSUO、ZHUANYEJIANDINGJIGOU,BAOKUOZHONGGUOSHENGWUZAINEIDEYANGQI、MINYINGQIYEJIGAOXIAODENG,XINGCHENGLEYIMIAOZONGHEXINGJISHUYANJIUKAIFADAPINGTAITIXI。

ANZHAOCHANGGUIDEYIMIAOSHENPINGSHENPILIUCHENG,LINCHUANGYANJIUZHEYAOXIANGGUOJIAYAOJIANBUMENTICHUYIMIAOYICIXINGLINCHUANGJIDISHENQING,JINGHEFAPIJIANHOUFANGKEJINXINGLINCHUANGSHIYAN。LINCHUANGYANGPINBIXUJINGZHONGGUOSHIPINYAOPINJIANDINGYANJIUYUANJIANDINGHEGE。LINCHUANGFANGANXUTONGGUODISANFANGLUNLIWEIYUANHUITONGGUOHEGUOJIAYAOSHENLINCHUANGZHUANJIARENKE,FANGKEKAIZHANLINCHUANGSHIYAN。

弘业股份“MUQIANDELIANFANGLIANKONGJIZHIXIA,XIANGGUANBUMENDESHENPINGSHENPIHESHENGCHANHUANJIEYIJINGBINGXINGTUIJIN。”XIANGGUANBUMENFUZERENBIAOSHI,PINGSHENBUMENYIJINGKAIZHANLEZAOQIJIERUGONGZUO,JINRUYANFA、SHIYANDEGEGEDEHUANJIE,JIYUJIANYIHEZHIDAO。LIRUZHONGGUOSHIPINYAOPINJIANDINGYANJIUYUANDEJISHUBIAOZHUNBUMEN、GUOJIAYAOPINJIANDUGUANLIZONGJUDESHENPINGZHONGXINDENGSHISHIGENJIN,QUEBAOKEYANSHUJUFUHEBIAOZHUN。

杨晓明表示:从产业化角度讲,我国是全球为数不多的几个品种齐全、质量优良、供应保障、且有一部分出口的疫苗生产国家之一;从研发创新的角度讲,通过这三个五年计划实施,以及863重大专项等支持,我国的疫苗研发创新实力不断提升,相信有效安全疫苗的研发将不会成为“马后炮”。

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